Efficacy： Pine bark extract is used to reduce the risk and severity of heart disease, strokes, high cholesterol, and circulation problems. It is used in the nutritional treatment of varicose veins and edema, which is swelling in the body due to fluid retention and leakage of blood vessels. Arthritis and inflammation have also been improved in studies using pine bark extract, as well as the uncomfortable symptoms of PMS and menopause. The OPCs in pine bark extract are recommended for various eye conditions that are caused by blood vessel damage, such as diabetic retinopathy and macular degeneration. Pine bark extract is recommended to improve the health and smoothness of the skin, including damage caused by overexposure to sunlight. Pine bark extract is a supplement used for anti-aging and preventive care as well.