Hydrophobic interaction chromatography (HIC) is a chromatographic method that uses the interaction between the hydrophobic groups carried by biological molecules and the hydrophobic ligands on the stationary phase to separate substances. Salt ions can destroy the hydration membrane on the surface of biomolecules and promote the binding between hydrophobic groups and ligands.

Diamond Butyl is based on high-rigidity agarose with weakly hydrophobic aliphatic butyl groups. It has low back pressure and fast flow velocity，and is suitable for large-scale separation and purification of highly hydrophobic biomolecules.

Product Characteristics

• HIC resin using Butyl as its ligands
• Suitable for the capture and intermediate purification of proteins, which require HIC resins with low and intermediate hydrophobicity
• High rigid agarose matrix, enjoys high flow rate and low back pressure
• Different binding capacity and selectivity compared with Butyl Bestarose FF resin

For more details, please visit: https://www.bestchrom.com/diamond-butyl/