An in-depth assessment of the application and value of powder flow testing in the optimisation of granulation processes.

A new eBook from Freeman Technology, a Micromeritics company and global leader in powder characterisation, explores the application of powder flow measurements for monitoring and optimising granulation processes. Granulation is a vital unit operation for many industries, notably the biological pharma sector, but endpoint detection and scale-up remain a challenge. ‘Powder Flow Testing for Granulation Processes’ focuses on the value of bulk powder characterisation within this context, notably dynamic powder testing, and includes a number of experimental studies highlighting the benefits it delivers. This latest addition to the Freeman literature library will be of interest to any scientist or engineer looking to apply granulation more efficiently, to manufacture products with the characteristics required for commercial success.

Freeman Technology – Powder Flow Testing for Granulation Processes

“Granulation underpins the performance of many commercial products, including foods, fertilisers and detergents,” said Jamie Clayton, Operations Director, Freeman Technology, “and important intermediates such as pharmaceutical tableting blends. However, optimisation remains a challenge for many powder processors. A defining distinction of dynamic testing is that it characterises granules via properties that correlate directly with performance, for example in a tablet press. It can therefore be used to set granule specifications that are independent of scale. This is an important benefit when it comes to scale-up and commercialisation.

Containing a wealth of information and presented in an easy-to-digest format, the new eBook includes:

• A discussion of motivations for granulation and how they affect which properties are most relevant for process monitoring.

• A review of alternative testing techniques for characterising granules, their strengths and limitations.

• Experimental studies highlighting the value of multi-faceted powder characterisation based on dynamic, shear and bulk powder property measurement.

We’re delighted to add this new eBook to our library and share the expertise we’ve developed in this vital area,” said Mr Clayton. “We know that customers value our expanding range of eBooks for their detailed and comprehensive coverage in key areas. We hope the latest addition will be of considerable value to anyone facing a granulation challenge.”

Download a complimentary copy of Powder Testing for Granulation here – https://www.freemantech.co.uk/learn/ebooks

Freeman Technology and Powder Rheometer are registered trademarks of Freeman Technology Ltd.

ABOUT FREEMAN TECHNOLOGY

Freeman Technology, a Micromeritics company, specialises in systems for measuring the flow properties of powders and has over 15 years’ experience in powder flow and powder characterisation. Expert teams provide comprehensive support alongside the company’s range of products.

Systems are installed around the world across a diverse range of industries. They deliver data that maximise process and product understanding, accelerating R&D and formulation towards successful commercialisation, and supporting the long term optimisation of powder processes. 

Freeman Technology is headquartered in Gloucestershire, UK, with operations and distribution partners in key global territories.

In 2007 the company received the Queen’s Award for Enterprise in Innovation and in 2012 the Queen’s Award for Enterprise in International Trade.

Author Biography - Tim Freeman, Managing Director, Freeman Technology

Tim Freeman is Managing Director of powder characterisation company Freeman Technology for whom he has worked since the late 1990s. He was instrumental in the design and continuing development of the FT4 Powder Rheometer? and the Uniaxial Powder Tester. Through his work with various professional bodies, and involvement in industry initiatives, Tim is an established contributor to wider developments in powder processing.

Tim has a degree in Mechatronics from the University of Sussex in the UK. He is a mentor on a number of project groups for the Engineering Research Center for Structured Organic Particulate Systems in the US and a frequent contributor to industry conferences in the area of powder characterisation and processing. A past Chair of the American Association of Pharmaceutical Scientists (AAPS) Process Analytical Technology Focus Group Tim is a member of the Editorial Advisory Board of Pharmaceutical Technology and features on the Industry Expert Panel in European Pharmaceutical Review magazine.  Tim is also a committee member of the Particle Technology Special Interest Group at the Institute of Chemical Engineers, Vice-Chair of the D18.24 sub-committee on the Characterisation and Handling of Powders and Bulk Solids at ASTM and a member of the United States Pharmacopeial (USP) General Chapters Physical Analysis Expert Committee (GC-PA EC).